Hastelloy C-22 Sanitary Tubing for Pharmaceutical Piping Systems
When it comes to corrosion-resistant performance in highly demanding sanitary and pharmaceutical systems, DLX Alloy’s Hastelloy C-22 sanitary tubing delivers unmatched durability and chemical stability. Designed for environments where cleanliness and purity are critical, this nickel-chromium-molybdenum-tungsten alloy is engineered to resist the most aggressive oxidizing and reducing media. From pharmaceutical manufacturing to biotech and chemical processing, C-22 tubing ensures process integrity, longevity, and safety across multiple applications.
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Hastelloy C-22 is a nickel-based superalloy (UNS N06022 / W.Nr. 2.4602) developed for exceptional corrosion resistance. It’s widely recognized for its superior resistance to pitting, crevice corrosion, and stress cracking in both oxidizing and reducing environments. Unlike conventional stainless steels, it performs reliably in harsh acid mixtures and high-temperature clean-in-place (CIP) operations, which are common in modern pharmaceutical systems.
At DLX Alloy, we manufacture C-22 sanitary tubing with tight dimensional control, mirror-polished inner surfaces, and seamless welding integrity, ensuring each tube meets hygienic standards like ASTM B626, ASME SB-626, and ISO 1127.
Pharmaceutical production pipelines
Biotech and sterile process systems
Chemical reactors and acid transfer lines
Food and beverage hygienic systems
Clean energy and environmental equipment
Semiconductor and precision chemical industries
In these sectors, the tubing is essential for maintaining system purity while enduring aggressive cleaning and sterilization chemicals, such as nitric, phosphoric, or hydrochloric acids.
Specification
item | HC-276 | C-22 | C-4 | B2 | B3 | N |
C | ≤0.01 | ≤0.015 | ≤0.015 | ≤0.02 | ≤0.01 | 0.04-0.08 |
Mn | ≤1 | ≤0.5 | ≤1 | ≤1 | ≤3 | ≤1 |
Fe | 4-7 | 2-6 | ≤3 | ≤2 | ≤1.5 | ≤5 |
P | ≤0.04 | ≤0.02 | ≤0.04 | ≤0.04 | -- | ≤0.015 |
S | ≤0.03 | ≤0.02 | ≤0.03 | ≤0.03 | -- | ≤0.02 |
Si | ≤0.08 | ≤0.08 | ≤0.08 | ≤0.1 | ≤0.1 | ≤1 |
Ni | rest | rest | rest | rest | ≤65 | rest |
Co | ≤2.5 | ≤2.5 | ≤2 | ≤1 | ≤3 | ≤0.2 |
Ti+Cu | -- | -- | ≤0.7 | -- | ≤0.4 | ≤0.35 |
Al+Ti | -- | -- | -- | -- | ≤0.5 | ≤0.5 |
Cr | 14.5-16.5 | 20-22.5 | 14-18 | ≤1 | ≤1.5 | 6-8 |
Mo | 15-17 | 12.5-14.5 | 14-17 | 26-30 | ≤28.5 | 15-18 |
B | -- | -- | -- | -- | -- | ≤0.01 |
W | 3-4.5 | 2.5-3.5 | -- | -- | ≤3 | ≤0.5 |
V | ≤0.35 | ≤0.35 | -- | 0.2-0.4 | -- | ≤0.5 |
Shape | Size (mm) |
Wire | 0.5-7.5 |
Rod/Bar | 8.0-200 |
Strip | (0.5-2.5)*(5-180) |
Tube/Pipe | Custom made |
Sheet/Plate | Custom made |
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As global pharmaceutical and biotech industries continue to expand, there’s increasing demand for materials that combine hygienic design with chemical endurance. Stainless steel (304/316L) has long been a standard, but in processes where exposure to chlorides, oxidizers, or mixed acids occurs, these steels fall short. That’s where nickel-based alloys like Hastelloy C-22 stand out.
Recent market data shows a growing shift toward high-nickel sanitary alloys, particularly in sectors prioritizing contamination control and long-term operational stability. The trend is also driven by stricter FDA, GMP, and ISO regulations, requiring more reliable corrosion prevention and material traceability.
DLX Alloy has adapted to this trend by investing in precision manufacturing, CNC forming lines, and electropolishing systems specifically tailored for sanitary tubing. This ensures mirror-finish interiors, uniform wall thickness, and minimal contamination risk—qualities critical for pharmaceutical pipelines.
DLX Company Advantages
At DLX Alloy, we don’t just supply tubing — we engineer it for performance. Our advantages include:
Integrated Melting to Tubing Line – Complete in-house production ensures full material traceability.
High Purity Melts – Reduced sulfur and carbon content for enhanced corrosion resistance.
Advanced Surface Finishing – Ra ≤ 0.4 μm mirror polish for cleanability and reduced bacterial adhesion.
Custom Sizes and Grades – From 6mm to 219mm OD, available in C-22, C-276, and Alloy 625.
Precision Welding – Orbital TIG welding ensures 100% defect-free joints.
Global Compliance – Meets ASTM, ASME, ISO, and EN hygienic standards.
Quick Lead Time – Optimized logistics and consistent stock for fast delivery.
Engineering Support – Material selection guidance and corrosion analysis for complex systems.
These advantages allow DLX Alloy to serve pharmaceutical and biotech clients globally with confidence, consistency, and superior technical support.
Technical Comparison Table
| Property / Alloy | Hastelloy C-22 (UNS N06022) | 316L Stainless Steel | Alloy 625 (UNS N06625) | Hastelloy C-276 (UNS N10276) |
|---|---|---|---|---|
| Nickel Content (%) | 56 | 10–12 | 58 | 57 |
| Chromium (%) | 21 | 17–18 | 21 | 16 |
| Molybdenum (%) | 13 | 2–3 | 9 | 16 |
| Corrosion Resistance | Excellent (oxidizing & reducing) | Moderate | Excellent | Excellent |
| Max Operating Temp (°C) | 1250 | 900 | 980 | 1100 |
| Weldability | Excellent | Excellent | Good | Good |
| Applications | Pharma, chemical, biotech | Food, beverage | Marine, chemical | Chemical, pulp & paper |
| Cleanability (Ra) | ≤ 0.4 μm (sanitary finish) | 0.6–0.8 μm | ≤ 0.5 μm | ≤ 0.5 μm |
About Us:
Our 12,000㎡ factory is equipped with complete capabilities for research, production, testing, and packaging. We strictly adhere to ISO 9001 standards in our production processes, with an annual output of 1,200 tons. This ensures that we meet both quantity and quality demands. Furthermore, all products undergo rigorous simulated environment testing including high temperature, high pressure, and corrosion tests before being dispatched, ensuring they meet customer specifications.
For all our clients, we offer timely and multilingual after-sales support and technical consulting, helping you resolve any issues swiftly and efficiently.
Client Visits
Building Stronger Partnerships
We support all kinds of testing:
1. What makes Hastelloy C-22 suitable for pharmaceutical applications?
Because it resists aggressive acids and chloride-containing cleaning agents, maintaining hygienic integrity over long-term use.
2. How does DLX ensure hygienic surface quality?
Through precision electropolishing, ultrasonic cleaning, and Ra ≤ 0.4 μm surface finish to prevent microbial growth.
3. Is DLX C-22 tubing compatible with standard fittings?
Yes. It fits all sanitary ferrules, tri-clamps, and fittings conforming to ISO and ASME BPE standards.
4. Can it replace 316L stainless steel in existing systems?
Yes, especially in applications with aggressive chemical exposure or higher temperature cycles.
5. What testing is performed on DLX sanitary tubing?
Each tube undergoes eddy current, hydrostatic, and dimensional inspection before dispatch.
6. What is the typical delivery condition?
Bright annealed, pickled, or polished; with full traceability and material certificates (EN 10204 3.1).
7. Does DLX offer custom tube lengths?
Yes, standard lengths are 6m, but we also provide custom-cut lengths as per project requirements.
8. What industries use C-22 tubing the most?
Pharmaceuticals, biotechnology, chemical processing, and precision equipment manufacturing.
In today’s demanding sanitary and pharmaceutical industries, DLX Alloy’s Hastelloy C-22 sanitary tubing stands as a reliable, future-proof solution for critical pipeline systems. It not only ensures superior resistance against acids and chlorides but also guarantees the hygiene standards vital for pharmaceutical production.
With our advanced manufacturing lines, strict quality control, and deep material expertise, DLX continues to support clients worldwide in achieving higher efficiency, reliability, and compliance. For companies seeking dependable hygienic piping solutions, DLX C-22 sanitary tubing is a smart, long-term investment.
